河北醫(yī)科大學(xué)導(dǎo)師：倪志宇 正文

[導(dǎo)師姓名]
倪志宇

[所屬院校]
河北醫(yī)科大學(xué)

[基本信息]
導(dǎo)師姓名：倪志宇
性別：女
人氣指數(shù)：4928
所屬院校：河北醫(yī)科大學(xué)
所屬院系：
職稱：教授
導(dǎo)師類型：碩導(dǎo)
招生專業(yè)：法醫(yī)學(xué)

[通訊方式]
辦公電話：0311-86265602
電子郵件：nzy0603@126.com

[個(gè)人簡(jiǎn)述]
倪志宇，教授，副主任法醫(yī)師，碩士生導(dǎo)師。
河北醫(yī)科大學(xué)法醫(yī)學(xué)系法醫(yī)毒理與毒物分析教研室，研究方向：有毒植物單體成分的提取及毒理機(jī)制。發(fā)表SCI收錄論文20篇（第一作者6篇），累計(jì)影響因子63.44；CSCD收錄論文40余篇（第一作者12篇）；參編專著兩部；獲河北省高等教育教學(xué)成果一等獎(jiǎng)一項(xiàng)（第一完成人）、省科技進(jìn)步一等獎(jiǎng)一項(xiàng)（第七完成人）、省高等教育學(xué)會(huì)高等教育科學(xué)研究成果二等獎(jiǎng)兩項(xiàng)（第一完成人）、三等獎(jiǎng)一項(xiàng)（第一完成人）；2012年獲霍英東教育基金會(huì)第十三屆高等院校青年教師獎(jiǎng)，為河北省唯一獲獎(jiǎng)人；2012年獲河北青年五四獎(jiǎng)?wù)拢ㄈ」彩浂裙Γ?2008年度被評(píng)為河北省優(yōu)秀青年（全省共二十名，記三等功）；承擔(dān)科研及教學(xué)課題十六項(xiàng)。

[科研工作]
代表性論文:1. *Zhi-Yu Ni, Yong Li, Si-Ming Wang, Mei Dong and Qing-Wen Shi. Cancer- fighting Molecules-Taxol and its Analogs. Current Organic Chemistry. 2012, 16(17): 2038-2052 (IF=3.039) 2. *Zhi-Yu Ni, Mei Dong, Bin Cong, Man-Li Zhang, Yu-Fang Wang, Chang-Hong Huo, Qing-Wen Shi and Hiromasa Kiyota. A novel taxane 13-glucoside and other taxanes from the leaves of Taxus cuspidata. Planta Med. 2011, 77, 281-283 (IF=2.153) 3. *Zhi-Yu Ni, Yi-Bing Wu, Man-Li Zhang, Yu-Fang Wang, Mei Dong, Chang- Hong Huo, Qing-Wen Shi, Yu-Cheng Gu, Hiromasa Kiyota, Bin Cong. Novel taxa-4(20),12-diene and 2(3→20)abeotaxane from the needles of Taxus canadensis. Biosci. Biotichnol. Biochem. 2011, 75(9), 1698-1701 (IF=1.276)4. *Zhi-Yu Ni, Yi-Bing Wu, Mei Dong, Man-Li Zhang, Yu-Fang Wang, Francoise Sauriol, Chang-Hong Huo, Qing-Wen Shi, Yu-Cheng Gu, Hiromasa Kiyota, and Bin Cong. Diabietane ether, a new dimeric abietane with an ether linkage from Taxus cuspidata needles. Z. Naturforsch. 2011, 66b, 1083-1086 (IF=0.864)5. *Zhi-Yu Ni, Yi-Bing Wu, Kai Zhang, Mei Dong, Fran?oise Saurio, Chang-Hong Huo, Yu-Cheng Gu, Qing-Wen Shi. A monoterpene and two sesquiterpenoids from the flower of Achillea millefolium. Chemistry of Natrual Compounds. 2013, 49(3): 450-453 (IF=0.599)6. *Zhi-Yu Ni, Yuta Nagashima, Man-Li Zhang, Yu-Fang Wang, Mei Dong, Francoise Sauriol, Chang-Hong Huo, Qing-Wen Shi, Yu-Cheng Gu and and Hiromasa Kiyota. 11-Hydroxyisocom-2-en-5-one, a new sesquiterpenoid from Echinops spinosissimus. Chemistry of Natrual Compounds. 2013, 49(4): 632-634 (IF=0.599)7. *Yi-Bing Wu, Zhi-Yu Ni, Qing-Wen Shi, Mei Dong, Hiromasa Kiyota, Yu-Cheng Gu and Bin Cong. Constituents from Salvia Species and Their Biological Activities. Chem. Rev. 2012, 112(11): 5967-6026 (IF=41.298)8. *Shu-Hong Yu, Zhi-Yu Ni, Jing Zhang, Mei Dong, Francoise Sauriol, Chang- Hong Huo, Qing-Wen Shi, Yu-Cheng Gu, Hiromasa Kiyota and Bin Cong. Taxusecone, a novel Taxane with an unprecedented 11,12-Secotaxane skeleton from Taxus cuspidata needles. Biosci. Biotechnol. Biochem. 2009, 73(3): 756-758 (IF=1.326)9. *Yi-Bing Wu, Zhi-Yu Ni, Chang-Hong Huo, Jian Su, Mei Dong, Francoise Sauriol, Qing-Wen Shi, Yu-Cheng Gu and Hiromasa Kiyota. Xylomexicanins C and D, New Mexicanolide-Type Limonoeds from Xylocarpus granatum. Biosci. Biotechnol. Biochem., 2013, 77(4): 736-740 (IF=1.276)10. *Man-Li Zhang, Zhi-Yu Ni, Cun-Fang Li, Yu-Fang Wang, Mei Dong, Francoise Sauriol, Chang-Hong Huo, Qing-Wen Shi, Yeiko Yamada, Hiromasa Kiyota, Yu-Cheng Gu and Bin Cong. A new germacrane sesquiterpenolide lsolated from Artemisia frigida. Chemistry of Natrual Compounds. 2013. 49(4): 626-628 (IF=0.599)11. Yong Li, Zhi-Yu Ni, Rui-Xia Guo, Yi-Bing Wu, Mei Dong, Francoise Sauriol, Qing-Wen Shi, Yu-Cheng Gu and Bin Cong. A new taxane from the needles of Taxus cuspidata. Chemistry of Natural Compounds. 2013, 49(2): 277-280 (IF=0.599) 12. Man-Li Zhang, Zhi-Yu Ni, Yong Li, Yu-Fang Wang, Mei Dong, Li-Geng Li, Francoise Sauriol, Chang-Hong Huo, Qing-Wen Shi and Hiromasa Kiyota. A new taxane from Taxus canadensis needles. Chemistry of Natural Compounds, 2012, 47(6): 911-913 (IF=0.599)13. Yong Li, Zhi-Yu Ni, Meng-Chu Zhu, Kai Zhang, Yi-Bing Wu, Mei Dong, Qing-Wen Shi, Chang-Hong Huo, Francoise Sauriol, Hiromasa Kiyota, Yu-Cheng Gu and Bin Cong. Millifolides A-C. New 1,10-seco-guaianolides from the Flowers of Achilles millefolium. Z. Naturforsch. 2012. 67b: 438-446 (IF=0.899)14. Yu-Fang Wang, Zhi-Yu Ni, Mei Dong, Bin Cong, Qing-Wen Shi, Yu-Cheng Gu, and Hiromasa Kiyota. Secondary Metabolites of Plants from the Genus Saussurea: Chemistry and Biological Activity. Chemistry & Biodiversity. 2010, 7(11): 2623-2659 (IF=1.926)15. Yu Fang, Zhi-Yu Ni, Teiyiko Tamada, Yu-Fang Wang, Man-Li Zhang, Mei Dong, Bin Cong, Francoise Sauriol, Chang-Hong Huo, Qing-Wen Shi, Hiromasa Kiyota, Two new phytoecdysteroids from the needles of Taxus canadensis. Z. Naturforsch. 2010, 65b, 1401-1405 (IF=0.816) 16. Shu-Jin Li, Zhi-Yu Ni, Cong Bin, Wei-Juan Gao, Shun-Jiang Xu, Chun-Yan Wang, Yu-Xia Yao, Chun-Ling Ma, and Yi-Ling Ling. CCK-8 inhibits LPS-induced IL-1β production in pulmonary interstitial macrophages by PKA, P38, NF-κB pathway. Shock. 2007, 27(6): 678-686 (IF=3.325)17. 倪志宇, 叢斌, 董玫, 馬春玲, 李淑瑾, 付麗紅, 張曉靜, 文迪. 八肽膽囊收縮素通過(guò) p38MAPK 通路抑制LPS誘導(dǎo)的RAW264.7 細(xì)胞IL-β 表達(dá). 中國(guó)藥理學(xué)通報(bào), 2011, 27(7): 971-975 (CSCD)18. 倪志宇, 董玫, 文迪, 李淑瑾, 叢斌. 八肽膽囊收縮素抑制LPS誘導(dǎo)的RAW264.7 細(xì)胞AP-1活性及IL-6表達(dá). 中國(guó)藥理學(xué)通報(bào), 2011, 27(11): 1578-1582 (CSCD)19. 倪志宇, 叢斌, 董玫, 馬春玲, 李淑瑾, 文迪. 八肽膽囊收縮素對(duì)脂多糖誘導(dǎo)RAW264.7 細(xì)胞IL-1、IL-6、IL-10表達(dá)的影響. 第三軍醫(yī)大學(xué)學(xué)報(bào), 2011, 33(22): 2366-2369 (CSCD) 20. 倪志宇, 叢斌, 李淑瑾, 馬春玲, 閆玉仙, 徐錦榮, 張國(guó)忠. CCK-8對(duì)LPS攻擊小鼠IL-1β、IL-6、IL-4、IL-10表達(dá)的影響. 中國(guó)病理生理雜志, 2007, 23(2): 331-335

[教育背景]
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