中國農(nóng)業(yè)大學(xué)農(nóng)學(xué)與生物技術(shù)學(xué)院博導(dǎo):徐明良

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中國農(nóng)業(yè)大學(xué)農(nóng)學(xué)與生物技術(shù)學(xué)院博導(dǎo):徐明良

中國農(nóng)業(yè)大學(xué)農(nóng)學(xué)與生物技術(shù)學(xué)院博導(dǎo):徐明良內(nèi)容如下,更多考研資訊請關(guān)注我們網(wǎng)站的更新!敬請收藏本站,或下載我們的考研派APP和考研派微信公眾號(里面有非常多的免費(fèi)考研資源可以領(lǐng)取,有各種考研問題,也可直接加我們網(wǎng)站上的研究生學(xué)姐微信,全程免費(fèi)答疑,助各位考研一臂之力,爭取早日考上理想中的研究生院校。)

中國農(nóng)業(yè)大學(xué)農(nóng)學(xué)與生物技術(shù)學(xué)院博導(dǎo):徐明良 正文

  基本信息
  姓名:徐明良
  性別:男
  系別: 植物遺傳育種學(xué)系
  職稱:教授
  學(xué)位:博士

  個人簡歷
  1964年2月出生, 籍貫寧波。
  1980年9月-1984年7月,浙江農(nóng)業(yè)大學(xué)寧波分校,獲農(nóng)學(xué)學(xué)士學(xué)位。
  1984年9月-1987年7月,原江蘇農(nóng)學(xué)院,獲農(nóng)學(xué)碩士學(xué)位。
  1987年7月-2003年9月,揚(yáng)州大學(xué),助教、講師、副教授、教授、博士生導(dǎo)師
  1993年9月-1996年7月,復(fù)旦大學(xué),獲理學(xué)博士學(xué)位
  1997年2月-1999年2月,德國Hohenheim大學(xué),博士后
  1999年2月-2002年6月,美國Illinois大學(xué),博士后
  2003年- 中國農(nóng)業(yè)大學(xué),教授,博士生導(dǎo)師
  新世紀(jì)百千萬人才工程國家級人選
  國家杰出青年基金獲得者

  聯(lián)系方式
  辦公室電話:010-62733166
  實(shí)驗(yàn)室電話:010-62731135
  傳真:010-62733808
  電子郵件:mxu@cau.edu.cn
  郵寄地址:
  國家玉米改良中心,304室
  中國農(nóng)業(yè)大學(xué)
  北京市圓明園西路2號
  郵編 100193
  Mingliang Xu, Ph.D.
  Professor of Molecular Genetics & Biotechnology
  National Maize Improvement Center of China
  China Agricultural University
  2 West, Yuanmingyuan Rd.
  Beijing, 100094
  P.R. China
  Phone: 010-62733166 (Office)
  010-62731135 (Lab.)
  Fax: 010-62733808
  E-mail:mxu@cau.edu.cn

  社會職務(wù)
  《Theoretical and Applied Genetics》編委
  《Plant Molecular Biology Reporter》編委
  《Journal of Genetics and Genomics》編委
  《作物學(xué)報》編委
  《玉米科學(xué)》編委
  《生物工程學(xué)報》編委
  中國作物學(xué)會理事

  教學(xué)工作
  分子生物學(xué)導(dǎo)論,32學(xué)時,主講,碩士研究生
  作物科學(xué)研究進(jìn)展,4學(xué)時,講座,博士研究生

  研究方向
  玉米、水稻和蘋果等作物的功能基因組
  在玉米全基因組范圍內(nèi)篩選出了抗病和防御相關(guān)的候選基因300多個,并將他們定位到玉米基因組上,這一工作的完成為玉米各種抗病基因的克隆提供了材料、信息和技術(shù)平臺;發(fā)展了一套全新的分離玉米Mu突變體旁鄰序列方法,為玉米功能基因大規(guī)??寺〉於嘶A(chǔ);克隆了玉米抗甘蔗花葉病毒病候選基因,已獲得轉(zhuǎn)基因植株,開展功能互補(bǔ)鑒定;完成抗青枯病、絲黑穗病基因的定位和基因區(qū)域高密度分子標(biāo)記的發(fā)展,克隆候選基因,開展功能  互補(bǔ)鑒定;構(gòu)建了玉米抗病自交系FAP1360、1145等的BAC庫。
  在水稻中克隆了水稻廣親和基因、米香性狀基因;研究了參與淀粉合成各個基因與稻米品質(zhì)的關(guān)系,證明Waxy基因同時控制直鏈淀粉含量和膠稠度,可溶性淀粉合成酶基因SSIIa 控制糊化溫度。
  在蘋果中克隆到了二個抗斑點(diǎn)病基因Vfa1 和Vfa2,體外構(gòu)建了結(jié)合Vfa1 和Vfa2的‘超級’抗病基因。針對蘋果等信息量極少的作物上開展圖位克隆的相關(guān)技術(shù)進(jìn)行了廣泛的探討。

  課題項(xiàng)目
  共主持科研項(xiàng)目10項(xiàng),其中三項(xiàng)已完成
  已完成的課題:
  1. 玉米抗甘蔗花葉病毒基因的分離,中國-丹麥政府間科技合作項(xiàng)目,2004-2006,主持人。
  2. 基于水稻基因序列的品質(zhì)性狀主效QTL克隆,“863”項(xiàng)目,中國科技部,160萬,2002-2005,項(xiàng)目編號:2002AA224041,主持人。
  3.基于片段互換的蘋果斑點(diǎn)病基因功能域研究及體外“超級”抗病基因的構(gòu)建,國家自然基金項(xiàng)目,23萬,2004-2006。主持人。
  在研課題:
  1. 水稻重要米香物質(zhì)2-乙?;量┻?AP)的代謝研究, 國家自然基金,28萬
2008-2011, 項(xiàng)目編號:30771318, 主持人。
  2. 主要動植物功能基因組研究-玉米抗病、抗逆、品質(zhì)的功能基因組研究,
“863”重大項(xiàng)目, 348萬, 2006-2010, 項(xiàng)目編號:2006AA10A107, 主持人。
  3. 玉米全基因組抗病相關(guān)基因連鎖圖譜的構(gòu)建和主要抗病基因的克隆,
杰青項(xiàng)目, 160萬, 2006-2009, 項(xiàng)目編號:30525035, 主持人。
  4. 玉米第六染色體抗病基因富集區(qū)的功能基因組研究, 北京市基金項(xiàng)目, 90萬, 2006-2009, 項(xiàng)目編號:50060001, 主持人。
  5. 中國玉米標(biāo)準(zhǔn)DNA指紋庫構(gòu)建及關(guān)鍵技術(shù)研究, 北京基礎(chǔ)平臺項(xiàng)目, 60萬, 2008-2010, 項(xiàng)目編號:YZPT02-06, 主持人。
  6. 玉米大豆高產(chǎn)優(yōu)質(zhì)品種分子設(shè)計(jì)和選育基礎(chǔ)研究“973”計(jì)劃項(xiàng)目,100萬,項(xiàng)目編號:2009CB118401,參加人。
  7. 轉(zhuǎn)基因玉米抗病材料的創(chuàng)新和新品種的培育-玉米抗病基因克隆、改造和轉(zhuǎn)化,轉(zhuǎn)基因生物新品種培育科技重大專項(xiàng),450萬,項(xiàng)目編號:2009ZX08003-013B,主持人。

  論文著作
  2010年(*通訊作者)
  1.Qing Ji, Jufei Lu, Qing Chao, Yan Zhang, Meijing Zhang, Minghong Gu,
Mingliang Xu*. 2010. Two sequence alterations, a 136-bp InDel and an A/C polymorphic site, in the S5 locus are associated with compatibility of indica/japonica hybrid in rice. J. Genet. Genomics 37
  2.Qin Yang, Guangming Yin, Yanling Guo, Dongfeng Zhang, Shaojiang Chen, Mingliang Xu*. 2010. A major QTL for resistance to Gibberella stalk rot in maize. Theor Appl Genet 121:673
  3.Lai JS, Li RQ, Xu X, Jin WW, Xu ML, Zhao HN, Xiang ZK, Song WB, Ying K, Zhang M, Jiao YP, Ni PX, Zhang JG, Li D, Guo XS, Ye KX, Jian M, Wang B, Zheng HS, Liang HQ, Zhang XQ, Wang SC, Cheng SJ, Li JS, Fu Y, Springer NM, Yang HM, Wang JA, Dai JR, Schnable PS, and Wang J. Genome-wide patterns of genetic variation among elite maize inbred lines. Nature Genetics, 2010, 42:1027-1030. (共同第一作者)
  2009年
  1. Usarowska A, Dionisio G, Sarholz B, Piepho HP, Xu ML, Ingvardsen CR, Wenzel G, Lübberstedt T. 2009. Validation of candidate genes putatively associated with resistance to SCMV and MDMV in maize (Zea mays L.) by expression profiling. BMC Plant Biology 2009, 9:15 doi:10.1186/1471-2229-9-15
  2008年
  1. Soria-Guerra R, Xu ML, Korban S. 2008. Transgenic apple lines carrying vfa genes in tandem for resistance to apple scab. Hortscience 43:1156-1156.
  2. Chen YS, Chao Q, Tan GQ, Zhao J, Zhang MJ, Ji Q, and Xu ML*. 2008. Identification and fine-mapping of a major QTL conferring resistance against head smut in maize. Theor Appl Genet,117:1241.
  3. Chen JJ, Ding JH, Ouyang YD, Du HY, Yang JY, Cheng K, Zhao J, Qiu SQ, Zhang XL, Yao JL, Liu KD, Wang L, CG Xu, Li XH, Xue YB, Xia M, Ji Q, Lu JF, Xu ML, and Zhang QF. 2008. A tri-allelic system of S5 is a major regulator of the reproductive barrier and compatibility of indica-japonica hybrids in rice. Proc Natl Acad Sci 105: 11436-11441
  4. Jiang L, Ingvardsen CR, Lubberstedt T, Xu ML*. 2008. The Pic19 NBS-LRR gene family members are closely linked to Scmv1, but not involved in maize resistance to sugarcane mosaic virus. Genome, 51:673-684.
  5. Chen SH, Yang Y, Shi WW, Ji Q, He F, Zhang ZD, Cheng ZK, Liu XN, and Xu ML*. 2008. Badh2, encoding betaine aldehyde dehydrogenase, inhibits the biosynthesis of 2-acetyl-1-pyrroline, a major component in rice fragrance. Plant Cell 20: 1850-1861
  6. Wen WE, Li GQ, He ZH, Yang WY, Xu ML, Xia XC. 2008. Development of an STS marker closely linked to Yr26 against wheat stripe rust using the resistance gene-analog polymorphism (RGAP) technique. Mol Breed 22:507-515
  7. Wang YJ, Yin GM, Yang Q, Tang JH, Lu XM, Korban SS, Xu ML*. 2008. Identification and isolation of Mu-flanking fragments from maize. J of Genetics and Genomics 35: 207-213
  8. Malnoy M, Xu ML, Borejsza-Wysocka E, Korban SS, and Aldwinckle HS. 2008. Two receptor-like genes, Vfa1 and Vfa2, confer resistance to the fungal pathogen Venturia inaequalis inciting apple scab disease. Mol Plant-Microbe Interact 21:448-458. (共同第一作者)
  9. Shi WW, Yang Y, Chen SH, Xu ML*. 2008. Discovery of a new fragrance allele and the development of functional markers for the breeding of fragrant rice varieties. Mol Breed 22:185-192.
  Before 2007年
  1. Xiao WK, Zhao J, Fan SC, Li L, Dai JR, Xu ML*. 2007. Mapping of genome-wide resistance gene analogs (RGAs) in maize (Zea mays L.). Theor Appl Genet. 115:501-508.
  2. Wang GX, Chen Y, Zhao JR, Li L, Korban SS, Wang FG, Dai JR, Xu ML*. 2007. Mapping of defense response gene homologues and their association with resistance loci in maize. Journal of Integrative Plant Biology 49:1580-1598.
  3. Han YP, Gasic K, Sun FJ, Xu ML, Korban SS. 2006. A gene encoding starching branching enzyme I (SBEI) in apple (Malus × domestica, Rosaceae) and its phylogenetic relationship to Sbe genes from other angiosperms. Molecular Phylogenetics and Evolution 43:852-863.
  4. Farrar K, Asp T, Lübberstedt T, Xu ML, Christiansen C, Thomas A, Humphreys M, Donnison I. 2006. Construction and utilization of two Lolium perenne BAC libraries. Mol Breed. 19:15-23.
  5. Chen SH, Wu J, Yang Y, Shi WW, Xu ML*. 2006. The fgr gene responsible for rice fragrance was restricted within 69kb. Plant Science 171:505-514.
  6. Xiao WK, Xu ML*, Zhao JR, Wang FG, Li JS, Dai JR. 2006. Genome-wide isolation of resistance gene analogs in maize (Zea mays L.) Theor Appl Genet. 113:63-72.
  7. He Y, Han YP, Jiang L, Xu CW, Lu JF, Xu ML*. 2006. Functional analysis of starch-synthesis genes in determining rice eating and cooking qualities. Mol Breed 18:277-290.
  8. Ji Q, Lu JF, Chao Q, Gu MH, Xu ML*. 2005. Delimiting a rice wide-compatibility gene S 5 n to a 50 kb region. Theor Appl Genet 111: 1495- 1503.
  9. Xu ML, Li X and Korban SS, 2004. DNA methylation alterations and exchanges during in vitro cellular differentiation in rose (Rosa hybrida L.). Theor Appl Genet 109:899-910.
  10. Xu ML and Korban SS, 2004. Somatic variation plays a key role in driving the evolution of the Vf gene family that confer resistance to apple scab disease. Molecular Phylogenetics and Evolution 32:57-65.
  11. Huaracha, E.M., Xu ML, K. Gasic, E. Pauwels, A. van den Putte, J.W. Keulemans, and S.S. Korban. 2004. Phenotypic reaction and genetic analysis using AFLP-derived SCARs for resistance to apple scab. J. Phytopathology 152:260-266.
  12. Han YP, Xu ML*, Liu XY, Yan CJ, Korban SS, Chen XL and Gu MH.2004. Genes coding for starch branching enzymes are major contributors to starch viscosity characteristics in waxy rice (Oryza sativa L.). Plant Science 166:357-364.
  13. Liu XY, Gu MH, Han YP, Ji Q, Lu JF, Gu SL, Zhang R, Li X, Chen JM, Korban S S and Xu ML*. 2003. Developing gene-tagged molecular markers for functional analysis of starch-synthesizing genes in rice (Oryza Sativa L.). Euphytica 135:345-353.
  14. Xu ML and Korban SS. 2003. Positional cloning of the apple scab resistance gene Vf. Proc. XXVII Intl. Hort. Cong. Acta Hort. 625:79-87.
  15. Carr J, Xu ML and Korban SS. 2003. Estimating genetic diversity in New Guinea impatiens. Proc. XXVII Intl. Hort. Cong. 623:161-168.
  16. Dußle C, Quin M, Melchinger AE, Xu ML and Luebberstedt T, 2003. Saturation of two chromosome regions conferring resistance to SCMV by targeted BSA. Theor Appl Genet 106:485-493.
  17. Carr, J., Xu ML, J.W. Dudley, and S.S. Korban. 2003. AFLP analysis of genetic variability in New Guinea impatiens. Theor Appl Genet 106: 1509-1516.
  18. Huaracha E, Xu ML, Pauwels E, Keulemans W and Korban SS, 2002. Comparison of marker-assisted selection and phenotypic selection for apple scab resistance in a set of apple progenies Theor Appl Genet 108:274-479.
  19. Li XQ, Xu ML and Korban SS, 2002. DNA methylation profiles differ between field- and in vitro-grown leaves of apple. Journal of plant physiology 159:1229-1234.
  20. Xu ML and Korban SS, 2002. A cluster of four active receptor-like genes reside in the Vf locus that confers resistance to apple scab disease. Genetics 162:1995-2006.
  21. Dußle CM, Quint M, Xu ML, Melchinger AE and Luebberstedt T, 2002. Conversion of AFLP fragments tightly linked to SCMV resistance genes Scmv1 and Scmv2 into simple PCR-based markers. Theor Appl Genet 105: 1190-1195.
  22. Quint M, Mihaljevic R, Dußle CM, Xu ML, Melchinger AE and Luebberstedt T, 2002. Genetic mapping of candidate genes for SCMV resistance in maize and conversion into RGA-CAPS markers. Theor Appl Genet 105:355-363.
  23. Xu ML and Korban SS, 2002. AFLP-derived SCARs facilitate construction of a 1.1 Mb sequence-ready map of a region that spans the Vf locus in the apple genome. Plant Mol Biology 50: 803-818.
  24. Korban SS and Xu ML, 2002. Going after the scab resistance gene. Trans. Ill. Hort. Soc. 134:15-20.
  25. Xu ML, Korban SS, Song JQ, and Jiang JM 2002. Constructing a bacterial artificial chromosome library of the apple cultivar GoldRush. Acta Hort. 595:103-112.
  26. Xu ML, Song JQ, Cheng ZK, Jiang JM and Korban SS, 2001. A bacterial artificial chromosome (BAC) library of Malus floribunda 821 and contig construction for positional cloning of the apple scab resistance gene Vf. Genome 44:1104-1113.
  27. Xu ML, Huaracha E and Korban SS, 2001. Development of sequence-characterized amplified regions (SCARs) from amplified fragment length polymorphism (AFLP) markers tightly linked to the Vf gene in apple. Genome 44:63-70.
  28. Xu ML, Li XQ and Korban SS, 2000. AFLP-based detection of DNA methylation. Plant Mol Biol
Rep 18: 361-368.
  29. Xu ML and Korban SS, 2000. Saturation mapping of the apple scab resistance gene Vf using AFLP markers. Theor Appl Genet 101: 844-851.
  30. Xu ML, Melchinger AE and Luebberstedt T, 2000. Origin of Scm1 and Scm2 - two loci conferring resistance to sugarcane mosaic virus (SCMV)in maize. Theor Appl Genet 100: 934-941.
  31. Luebberstedt T, Xia XC, Xu ML, Kuntze L, Melchinger AE, 1999. Inheritance of resistance to SCMV and MDMV in European maize. In: Proc. of the XVth EUCARPIA 1998 General Congress: Genetics and breeding for crop quality and resistance, G.T.S. Mugnozza (ed.), pp. 241-250 Kluwer
Academic Publishers, Dordrecht, The Netherlands
  32. Xu ML, Melchinger AE, Xia XC and Luebberstedt T, 1999. High-resolution mapping of loci conferring resistance to sugarcane mosaic virus in maize using RFLP, SSR, and AFLP markers. Mol Gen Genet 261: 574-581.
  33. Xu ML, Melchinger AE and Luebberstedt T, 1999. Species-specific detection of the maize pathogens Sporisorium reiliana and Ustilago maydis by dot blot hybridization and PCR-based
assays. Plant Dis 83: 390-395.

  獎勵情況
  1.“稻、麥、玉米抗病性遺傳分析”,“七。五”農(nóng)業(yè)部重點(diǎn)研究項(xiàng)目,1991,農(nóng)業(yè)部科技進(jìn)步三等獎。
  2.“玉米、小麥雄性不育雜種優(yōu)勢利用和群體改良基礎(chǔ)理論研究”,1992, 江蘇省科學(xué)技術(shù)進(jìn)步三等獎,第三完成人。
  3.“玉米不育化雜交種-蘇玉6號”1994,江蘇省科學(xué)技術(shù)進(jìn)步二等獎,第四完成人。
  4.“玉米不育化雜交種-蘇玉6號”1994,江蘇省農(nóng)林廳一等獎,第四完成人。
  5.“基于YAC庫的水稻線粒體基因組分析和不育相關(guān)區(qū)段探索”,1998,霍英東基金會優(yōu)秀高校青年教師基金。
  6. “玉米新型不育系J7(YⅡ-1)育性歸群鑒定理論及其應(yīng)用研究”,2005,江蘇省科學(xué)技術(shù)進(jìn)步三等獎,第三完成人。
   

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