沈陽(yáng)藥科大學(xué)中藥學(xué)院導(dǎo)師：姚新生 正文

[導(dǎo)師姓名]
姚新生

[所屬院校]
沈陽(yáng)藥科大學(xué)

[基本信息]
導(dǎo)師姓名：姚新生
性別：男
人氣指數(shù)：1591
所屬院校：沈陽(yáng)藥科大學(xué)
所屬院系：中藥學(xué)院
職稱：教授
導(dǎo)師類型：碩導(dǎo)/博導(dǎo)
招生專業(yè)：天然藥物化學(xué)、藥學(xué)（天然藥物化學(xué)方向）
研究領(lǐng)域：一：中藥及天然藥物（包括微生物次生代謝產(chǎn)物研究）活性成分研究研究方向二：中藥（特別是復(fù)方）...

[通訊方式]
辦公電話：024-23993994
電子郵件：tyaoxs@gmail.com
通訊地址：沈陽(yáng)市沈河區(qū)文化路103號(hào)81號(hào)信箱

[個(gè)人簡(jiǎn)述]
姚新生，男，博士，中國(guó)工程院院士，沈陽(yáng)藥科大學(xué)教授，暨南大學(xué)藥學(xué)院名譽(yù)院長(zhǎng)。1949年5月上海解放后參加黨的外圍組織—青年先鋒隊(duì)。1950年12月響應(yīng)黨和政府號(hào)召，報(bào)名參加軍事干部學(xué)校，被軍委送至中國(guó)醫(yī)科大學(xué)軍醫(yī)一期、后改為東北藥學(xué)院軍藥二十三期學(xué)習(xí)。1955年7月東北藥學(xué)院（現(xiàn)沈陽(yáng)藥科大學(xué)）畢業(yè)，留校任教至今。1981年6月10日-1983年6月10日去日本東京大學(xué)留學(xué)，獲藥學(xué)博士學(xué)位。1996年當(dāng)選為中國(guó)工程院院士。長(zhǎng)期從事中藥與天然藥物化學(xué)教學(xué)及科研工作。已培養(yǎng)了68名博士(1名教育部全國(guó)百名優(yōu)秀博士)、47名碩士、9名博士后；正培養(yǎng)博士生19人、碩士生18人、博士后4人。迄今已在國(guó)內(nèi)外學(xué)術(shù)刊物上發(fā)表了400余篇文章，1986年以來(lái)已有320余篇被SCI收錄，他引2432次，每項(xiàng)平均引用次數(shù)：9.49，h-index：25。主編出版了《天然藥物化學(xué)》、《有機(jī)化合物波譜解析》以及《超導(dǎo)核磁共振波譜解析》等三部全國(guó)醫(yī)藥院校統(tǒng)編教材及研究生教材；申請(qǐng)了79項(xiàng)專利，已獲授權(quán)16項(xiàng)，成功研制開發(fā)新藥4個(gè)。獲省部級(jí)以上獎(jiǎng)勵(lì)5項(xiàng)。2007年9月中國(guó)藥學(xué)會(huì)百年慶典大會(huì)上，由全國(guó)人大常務(wù)委員會(huì)副委員長(zhǎng)、全國(guó)科協(xié)主席韓啟德授予中國(guó)藥學(xué)會(huì)突出貢獻(xiàn)獎(jiǎng)。

[科研工作]
近年來(lái)發(fā)表代表性論文1. An, Y.N. Zhang, X. Zhang, T.Y. Zhang, M.Y. Zhang, Q. Deng, X.Y. Zhao, F. Zhu, L.J. Wang, G. Zhang, J. Zhang, Y.X.* Liu, B.* Yao, X.S.* Penicimenolides A-F, Resorcylic Acid Lactones from Penicillium sp., Isolated from the Rhizosphere Soil of Panax notoginseng. Sci. Rep., 2016, 6, 27396. (IF=5.228)2. Tian, W.J. Qiu, Y.Q. Yao, X.J. Chen, H.F. Dai, Y.* Zhang, X.K. Yao, X.S.* Dioxasampsones A and B, Two Polycyclic Polyprenylated Acylphloroglucinols with Unusual Epoxy-Ring-Fused Skeleton from Hypericum sampsonii. Org. Lett., 2014,16, 6346-6349. (IF=6.364)3. Tian, W.J. Yu, Y. Yao, X.J. Chen, H.F. Dai, Y.* Zhang, X.K. Yao, X.S.* Norsampsones A-D, Four New Decarbonyl Polycyclic Polyprenylated Acylphloroglucinols from Hypericum sampsonii. Org. Lett., 2014, 16, 3448-3451. (IF=6.364)4. Tian, D.M. Cheng, H.Y. Jiang, M.M. Shen, W.Z. Tang, J.S.* Yao, X.S.* Cardiac Glycosides from the Seeds of Thevetia peruviana. J. Nat. Prod., 2016, 79, 38-50. (IF=3.662)5. Li, B. Ni, Y. Zhu, L.J. Wu, F.B. Yan, F. Zhang, X.* Yao, X.S.* Flavonoids from Matteuccia struthiopteris and Their Anti-influenza Virus (H1N1) Activity. J Nat. Prod., 2015, 78, 987-995. (IF=3.662)6. Wang, P.L. Yao, Z.H. Zhang, F.X. Shen, X.Y. Dai, Y.* Qin, L. Yao, X.S.* Identification of Metabolites of PSORALEAE FRUCTUS in Rats by Ultra Performance Liquid Chromatography Coupled with Quadrupole Time-of-flight Tandem Mass Spectrometry Analysis. J Pharm. Biomed. Anal., 2015, 112, 23-35. (IF=3.169)7. Geng, J.L. Dai, Y. Yao, Z.H.* Qin, Z.F. Wang, X.L. Qin, L. Yao, X.S.* Metabolites Profile of Xian-Ling-Gu-Bao Capsule, a Traditional Chinese Medicine Prescription, in Rats by Ultra Performance Liquid Chromatography Coupled with Quadrupole Time-of-flight Tandem Mass Spectrometry Analysis. J Pharm. Biomed. Anal., 2014, 96, 90-103. (IF=2.979)8. Tian, W.J. Qiu, Y.Q. Jin, X.J. Chen, H.F. Yao, X.J. Dai, Y.* Yao, X.S.* Novel Polycyclic Polyprenylated Acylphloroglucinols from Hypericum sampsonii. Tetrahedron, 2014, 70, 7912-7916. (IF=2.641)9. Li, C. Dai, Y. Zhang, S.X. Duan, Y.H. Liu, M.L. Chen, L.Y. Yao, X.S.* Quinoid Glycosides from Forsythia suspensa. Phytochemistry, 2014, 104, 105-113. (IF=2.547)10. Wang, G. Zhu, L.J. Zhao, Y.Q. Gao, S.Y. Sun, D.J. Yuan, J.Q. Huang, Y.X. Zhang, X.* Yao, X.S.* A Natural Product from Cannabis sativa subsp. sativa Inhibits Homeodomain-interacting Protein Kinase 2 (HIPK2), Attenuating MPP+-induced Apoptosis in Human Neuroblastoma SH-SY5Y cells. Bioorg. Chem., 2017, 72, 64-73. (IF=2.252)主編或參編的教材、專著1.《天然藥物化學(xué)》第二版主編，高等醫(yī)藥院校教材. 人民衛(wèi)生出版社. 1995年4月2.《有機(jī)化合物波譜解析》第一版主編，全國(guó)高等醫(yī)藥院校藥學(xué)類教材. 中國(guó)醫(yī)藥科技出版社. 2004年1月3.《超導(dǎo)核磁共振波譜分析》主編，中國(guó)醫(yī)藥科技出版社. 1991年10月 1. An, Y.N. Zhang, X. Zhang, T.Y. Zhang, M.Y. Zhang, Q. Deng, X.Y. Zhao, F. Zhu, L.J. Wang, G. Zhang, J. Zhang, Y.X.* Liu, B.* Yao, X.S.* Penicimenolides A-F, Resorcylic Acid Lactones from Penicillium sp., Isolated from the Rhizosphere Soil of Panax notoginseng. Sci. Rep., 2016, 6, 27396. (IF=5.228)2. Tian, W.J. Qiu, Y.Q. Yao, X.J. Chen, H.F. Dai, Y.* Zhang, X.K. Yao, X.S.* Dioxasampsones A and B, Two Polycyclic Polyprenylated Acylphloroglucinols with Unusual Epoxy-Ring-Fused Skeleton from Hypericum sampsonii. Org. Lett., 2014,16, 6346-6349. (IF=6.364)3. Tian, W.J. Yu, Y. Yao, X.J. Chen, H.F. Dai, Y.* Zhang, X.K. Yao, X.S.* Norsampsones A-D, Four New Decarbonyl Polycyclic Polyprenylated Acylphloroglucinols from Hypericum sampsonii. Org. Lett., 2014, 16, 3448-3451. (IF=6.364)4. Tian, D.M. Cheng, H.Y. Jiang, M.M. Shen, W.Z. Tang, J.S.* Yao, X.S.* Cardiac Glycosides from the Seeds of Thevetia peruviana. J. Nat. Prod., 2016, 79, 38-50. (IF=3.662)5. Li, B. Ni, Y. Zhu, L.J. Wu, F.B. Yan, F. Zhang, X.* Yao, X.S.* Flavonoids from Matteuccia struthiopteris and Their Anti-influenza Virus (H1N1) Activity. J Nat. Prod., 2015, 78, 987-995. (IF=3.662)6. Wang, P.L. Yao, Z.H. Zhang, F.X. Shen, X.Y. Dai, Y.* Qin, L. Yao, X.S.* Identification of Metabolites of PSORALEAE FRUCTUS in Rats by Ultra Performance Liquid Chromatography Coupled with Quadrupole Time-of-flight Tandem Mass Spectrometry Analysis. J Pharm. Biomed. Anal., 2015, 112, 23-35. (IF=3.169)7. Geng, J.L. Dai, Y. Yao, Z.H.* Qin, Z.F. Wang, X.L. Qin, L. Yao, X.S.* Metabolites Profile of Xian-Ling-Gu-Bao Capsule, a Traditional Chinese Medicine Prescription, in Rats by Ultra Performance Liquid Chromatography Coupled with Quadrupole Time-of-flight Tandem Mass Spectrometry Analysis. J Pharm. Biomed. Anal., 2014, 96, 90-103. (IF=2.979)8. Tian, W.J. Qiu, Y.Q. Jin, X.J. Chen, H.F. Yao, X.J. Dai, Y.* Yao, X.S.* Novel Polycyclic Polyprenylated Acylphloroglucinols from Hypericum sampsonii. Tetrahedron, 2014, 70, 7912-7916. (IF=2.641)9. Li, C. Dai, Y. Zhang, S.X. Duan, Y.H. Liu, M.L. Chen, L.Y. Yao, X.S.* Quinoid Glycosides from Forsythia suspensa. Phytochemistry, 2014, 104, 105-113. (IF=2.547)10. Wang, G. Zhu, L.J. Zhao, Y.Q. Gao, S.Y. Sun, D.J. Yuan, J.Q. Huang, Y.X. Zhang, X.* Yao, X.S.* A Natural Product from Cannabis sativa subsp. sativa Inhibits Homeodomain-interacting Protein Kinase 2 (HIPK2), Attenuating MPP+-induced Apoptosis in Human Neuroblastoma SH-SY5Y cells. Bioorg. Chem., 2017, 72, 64-73. (IF=2.252)主編或參編的教材、專著1.《天然藥物化學(xué)》第二版主編，高等醫(yī)藥院校教材. 人民衛(wèi)生出版社. 1995年4月2.《有機(jī)化合物波譜解析》第一版主編，全國(guó)高等醫(yī)藥院校藥學(xué)類教材. 中國(guó)醫(yī)藥科技出版社. 2004年1月3.《超導(dǎo)核磁共振波譜分析》主編，中國(guó)醫(yī)藥科技出版社. 1991年10月專利及其他1. 姚新生，張曉坤，戴毅，王光輝，張雪，陳海峰，段營(yíng)輝，陳杰波，靳三林. 一種組合物及其在制備 RXR 受體轉(zhuǎn)錄抑制劑中的應(yīng)用. ZL 201010191462.82. 姚新生，張曉坤，戴毅，王光輝，張雪，陳海峰，段營(yíng)輝，陳杰波，靳三林. 一種組合物及其在制備TR3受體誘導(dǎo)劑中的應(yīng)用. ZL 201010191471.73. 姚新生，張曉坤，姜苗苗，曾錦章，張雪，王光輝，戴毅，何加友. 誘導(dǎo)核受體TR3表達(dá)的強(qiáng)心苷類化合物及其應(yīng)用. ZL 200810027772.94. 楊寶峰，姚新生，馮速捷，張雪，侯云龍，王立艷，徐儉，朱玲娟. 一種治療缺血性心臟病及心律失常的中藥提取物及其制備方法.ZL201110131707.2

[教育背景]

沈陽(yáng)藥科大學(xué)

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