蘭州大學(xué)研究生導(dǎo)師：向云 正文

　　學(xué)習(xí)經(jīng)歷

　　1997.9--2001.7：甘肅農(nóng)業(yè)大學(xué)，學(xué)士

　　2001.9--2004.7：甘肅農(nóng)業(yè)大學(xué)，碩士

　　2004.9--2007.7：北京師范大學(xué)，博士

　　2008.5--2011.8：蘭州大學(xué)，在職博士后

　　2010.2--2011.8：美國(guó)杜克大學(xué)，訪問學(xué)者

　　工作經(jīng)歷

　　2007.7--2013.5：蘭州大學(xué)，副教授

　　2013.5--至今：蘭州大學(xué)，教授

　　教學(xué)及指導(dǎo)研究生情況

　　發(fā)表論文及專著

　　*代表通訊作者，#代表共同第一作者

　　[1] Yue Niu*, Dong Qian, Baiyun Liu, Jianchao Ma, Dongshi Wan, Xinyu Wang, Wenliang He, Yun Xiang*. ALA6, a P4-type ATPase, Is Involved in Heat Stress Responses in Arabidopsis thaliana. Frontiers in Plant Science, 2017, https://doi.org/10.3389/fpls.2017.01732.

　　[2] Hui Su*, Hualing Feng, Xiaoting Chao, Xia Ding, Qiong Nan, Chenxi Wen, Huidong Liu, Sinuo Liu, Yun Xiang*, Wenzhe Liu*, Fimbrins 4 and 5 Act Synergistically During Polarized Pollen-tube Growth to Ensure Fertility in Arabidopsis. Plant and Cell Physiology, 2017, https://doi.org/10.1093/pcp/pcx138.

　　[3] Jingen Zhu#, Qiong Nan#, Tao Qin#, Dong Qian, Tonglin Mao, Shunjie Yuan, Xiaorong Wu, Yue Niu, Qifeng Bai, Lizhe An, Yun Xiang*, Higher-ordered Actin Structures Remodeled by Arabidopsis ACTIN-DEPOLYMERIZING FACTOR5 Are Important for Pollen Germination and Pollen Tube Growth. Molecular Plant, 2017, 10: 1065-1081.

　　[4] Qiong Nan#, Dong Qian#, Yue Niu, Yongxing He, Shaofei Tong, Zhimin Niu, Jianchao Ma, Yang Yang, Lizhe An, Dongshi Wan*, Yun Xiang*, Plant Actin-depolymerizing Factors Possess Opposing Biochemical Properties Arising from Key Amino Acid Changes Throughout Evolution. Plant Cell, 2017, 29(2): 395-408. (Highlighted paper by Science Editor in “In Brief” )

　　Jennifer Lockhart, Loose-Knit Family: Tracing the Evolution of Actin-Depolymerizing Factors That Sever or Join the Actin Cytoskeleton. Plant Cell, 2017, 29 (2): 200-201, DOI: https://doi.org/10.1105/tpc.17.00088.

　　[5] Jiangtao Liu, Yuelong Zhou, Changxin Luo, Yun Xiang, Lizhe An*, De Novo Transcriptome Sequencing of Desert Herbaceous Achnatherum splendens (Achnatherum) Seedlings and Identification of Salt Tolerance Genes. Genes, 2016, 23: 7(4): 12.

　　[6] Hui Wang, Shengcheng Han, Wei Siao, Chunqing Song, Yun Xiang, Xiaorong Wu, Pengyu Cheng, Hongjuan Li, Ján Jásik, Karol Mi?ieta, Ján Turňa, Boris Voigt, Franti?ek Balu?ka, Jin Liu, Yingdian Wang, Heping Zhao*, Arabidopsis Synaptotagmin 2 Participates in Pollen Germination and Tube Growth and Is Delivered to Plasma Membrane via Conventional Secretion. Molecular Plant, 2015, 8(12):1737-1750.

　　[7] Dong Qian, Qiong Nan, Yang Yang, Hui Li, Yuelong Zhou, Jingen Zhu, Qifeng Bai, Pan Zhang, Lizhe An, Yun Xiang*, Gelsolin-Like Domain 3 Plays Vital Roles in Regulating the Activities of the Lily Villin/Gelsolin/Fragmin Superfamily. PLoS One, 2015, 10(11): e0143174.

　　[8] Jingen Zhu, Xiaorong Wu, Shunjie Yuan, Dong Qian, Qiong Nan, Lizhe An, Yun Xiang* (2014) Annexin5 Plays a Vital Role in Arabidopsis Pollen Development via Ca2+-Dependent Membrane Trafficking. PLoS One, 2014, 9(7): e102407.

　　[9] Jingen Zhu, Shunjie Yuan, Guo Wei, Dong Qian, Xiaorong Wu, Honglei Jia, Mengyuan Gui, Wenzhe Liu, Lizhe An*, Yun Xiang*, Annexin5 is Essential for Pollen Development in Arabidopsis. Molecular Plant, 2014, 7(4): 751-754.

　　[10] Honglei Jia, Jisheng Li, Jingen Zhu, Tingting Fan, Dong Qian, Yuelong Zhou, Jue Wang, Haiyun Ren, Yun Xiang*, Lizhe An*, Arabidopsis CROLIN1, a Novel Plant Actin-binding Protein, Functions in Cross-linking and Stabilizing Actin Filaments. Journal of Biological Chemisty, 2013, 288: 32277-32288.

　　[11] Tingting Fan, Huanhuan Zhai, Wenwei Shi, Jue Wang, Honglei Jia, Yun Xiang*, Lizhe An*, Overexpression of Profilin 3 Affects Cell Elongation and F-actin Organization in Arabidopsis thaliana. Plant Cell Reports, 2013, 32(1): 149-160.

　　[12] Binyun Ma, Dong Qian, Qiong Nan, Chang Tan, Lizhe An*, Yun Xiang*, Arabidopsis V-ATPase B Subunits Are Involved in Actin Cytoskeleton Remodeling via Binding to, Bundling and Stabilizing F-actin. Journal of Biological Chemisty, 2012, 287: 19008-19017.

　　[13] Jue Wang, Dong Qian, Tingting Fan, Honglei Jia, Lizhe An*, Yun Xiang*, Arabidopsis Actin Capping Protein (AtCP) Subunits Have Different Expression Patterns, and Downregulation of AtCPB Confers Increased Thermotolerance of Arabidopsis after Heat Shock Stress. Plant Science, 2012, 193: 110-119.

　　[14] Shanjin Huang, Yun Xiang, Haiyun Ren. (2011). Actin-binding Proteins and Actin Dynamics in Plant Cells. In The Plant Cytoskeleton, 2011, pp. 57-80. Springer New York.

　　[15] Binyun Ma, Yun Xiang, Lizhe An*, Structural Bases of Physiological Functions and Roles of the Vacuolar H+-ATPase. Cellular Signalling, 2011, 23: 1244-1256.

　　[16] Ting Wang#, Yun Xiang#, Jian Hou, Haiyun Ren*, ABP41 is Involved in the Pollen Tube Development via Fragmenting Actin Filaments. Molecular Plant, 2008, 1(6): 1048-1055.

　　[17] Yun Xiang, Xi Huang, Ting Wang, Yan Zhang, Qinwen Liu, Patrick J Hussey, Haiyun Ren*, ACTIN BINDING PROTEIN29 from Lilium Pollen Plays an Important Role in Dynamic Actin Remodeling. Plant Cell, 2007, 19(6): 1930-1946.

　　[18] Haiyun Ren*, Yun Xiang, The Function of Actin-binding Proteins in Pollen Tube Growth. Protoplasma, 2007, 230(3-4): 171-182.

　　研究方向

　　微絲骨架（actin cytoskeleton）是遍布于一切真核細(xì)胞中的三維網(wǎng)狀結(jié)構(gòu)，占植物總蛋白的15-20%，在維持細(xì)胞形態(tài)、參與細(xì)胞運(yùn)動(dòng)、胞質(zhì)分裂和極性建立等重要細(xì)胞生理活動(dòng)中起著決定性的作用。微絲骨架的動(dòng)態(tài)變化是其行使各種生理功能的基礎(chǔ)，而該過程則直接受到諸多微絲結(jié)合蛋白和不同信號(hào)分子的調(diào)控。本課題組以模式作物擬南芥為材料，主要開展如下研究工作：

　　1. 探索植物特有的、功能未知的微絲結(jié)合蛋白；

　　2. 微絲骨架參與植物花粉管極性生長(zhǎng)的分子機(jī)理；

　　3. 微絲骨架參與植物響應(yīng)各種非生物脅迫的分子機(jī)理；

　　4. 植物抗逆信號(hào)轉(zhuǎn)導(dǎo)（鈣離子）。

　　項(xiàng)目成果

　　1. 國(guó)家自然科學(xué)基金-優(yōu)秀青年科學(xué)基金項(xiàng)目，31722005，植物細(xì)胞骨架，2018/01-2020/12，在研，主持

　　2. 國(guó)家自然科學(xué)基金-面上項(xiàng)目，31670180，擬南芥微絲解聚因子第三亞家族成員生理生化功能研究，2017/01-2020/12，在研，主持

　　3. 國(guó)家自然科學(xué)基金-面上項(xiàng)目，31470283，擬南芥微絲交聯(lián)蛋白CROLINs調(diào)控花粉管生長(zhǎng)的分子機(jī)理研究，2015/01-2018/12，在研，主持

　　4. 教育部"新世紀(jì)優(yōu)秀人才支持計(jì)劃"，NCET-13-0264，植物細(xì)胞骨架，2014/01-2015/12，已結(jié)題，主持

　　5. 國(guó)家自然科學(xué)基金-面上項(xiàng)目，31270326，擬南芥液泡氫ATP酶B亞基不同異形體的生理生化功能及作用機(jī)理研究，2013/01-2016/12，已結(jié)題，主持

　　6. 甘肅省杰出青年基金，2013GS10064，微絲骨架參與植物響應(yīng)干旱和高鹽脅迫分子機(jī)理研究，2013/01-2015/12，已結(jié)題，主持

　　7. 國(guó)家自然科學(xué)基金-青年科學(xué)基金，30800079，擬南芥膜聯(lián)蛋白annexin5調(diào)控花粉管極性生長(zhǎng)的分子機(jī)制研究，2009/01-2011/12，已結(jié)題，主持

　　榮譽(yù)、獲獎(jiǎng)

　　1. 國(guó)家優(yōu)秀青年基金（2017）

　　2. 教育部"新世紀(jì)優(yōu)秀人才支持計(jì)劃"（2013）

　　3. 甘肅省杰出青年基金（2013）

 

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